Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
Mozambique tilapia Protein: Ore m 4 | Tropomyosin
Empirical Proteotypic Peptide Explorer:
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
Sequence - 284 amino acids
MDAIKKKMQMLKLDKENALDRAEQAESDKKAAEDRSKQLEDDLVALQKKLKGTEDELDKYSEALKDAQEKLELAEKIATDAEGEVASLNRRIQLVEEELDRAQERLATALTKLEEAEKAADESERGMKVIENRAMKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELSEGKCSELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKALTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
UniProt: K4PEK4 IUIS: Ore m 4Peptide Selector Tool
Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
Minimum length:
Maximum length:
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| R | AEQAESDK | K | 0 | 0.216 | 0.0853 |
| K | QLEDDLVALQK | K | 0 | 0.604 | 0.6873 |
| K | GTEDELDK | Y | 0 | 0.216 | 0.09108 |
| K | IATDAEGEVASLNR | R | 0 | 0.633 | 0.92352 |
| R | IQLVEEELDR | A | 0 | 0.48 | 0.63766 |
| R | LATALTK | L | 0 | 0.22 | 0.2594 |
| K | AADESER | G | 0 | 0.209 | 0.03304 |
| K | MELQEIQLK | E | 0 | 0.271 | 0.45026 |
| K | HIAEEADR | K | 0 | 0.296 | 0.2601 |
| K | LVIIEGDLER | T | 0 | 0.502 | 0.48278 |
| R | AELSEGK | C | 0 | 0.195 | 0.04786 |
| K | CSELEEELK | T | 0 | 0.297 | 0.43036 |
| K | TVTNNLK | S | 0 | 0.232 | 0.11856 |
| K | SLEAQAEK | Y | 0 | 0.229 | 0.31874 |
| K | TIDDLEDELYAQK | L | 0 | 0.627 | 0.58562 |
| K | AISEELDHALNDMTSI | $ | 0 | 0.485 | 0.4169 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.